Obstetric dating ultrasound
This has been further refined by looking at the nose bone of the baby with an additional blood test to identify two pregnancy hormones.This is the combined test and has achieved a predictive value of about 92%.The Harmony can now be used if the pregnancy is conceived with donated egg.The result of the Harmony is predictive to more than 99%.For the last ten years doctors have been using the results of the Nuchal Translucency Scan to advise pregnant women and their partners on their risk of having a baby with Downs syndrome, or other abnormalities.The Nuchal Translucency Scan looks at the skin fold on the back of the baby’s neck at about 12 weeks.
An increased nuchal translucency can also be normal.Anyone who is anxious about her baby having a chromosomal abnormality such as Downs, Edwards or Patau’s syndrome can have it. A good test result gives a risk of a chromosomal problem of less than 000. A risk of 1:2 requires an amniocentesis or chorionic villous sampling depending on the clinical situation. The test is currently £475 including the dating ultrasound scan.It is predicted that in 10 years it will become available for all on the NHS. On some occasions we can use a previous scan report, in which case the cost of the Harmony blood test would be £375.Women with a high risk have an option to proceed to chorion villous sampling (CVS) or amniocentesis. It has been discovered that a blood sample taken from the mother at any time from 10 weeks of pregnancy can be analysed for cell free fetal DNA, which is essentially a marker in the mother’s blood of the DNA of the baby.These are invasive tests that carry a miscarriage risk of about 0. The result of the simple blood test (Harmony) is predictive to more than 99%, which will hugely reduce the need for invasive testing by CVS or amniocentesis.
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Those who are very high risk may decide to proceed to an invasive procedure such as a CVS (Chorion Villus Sample) or if the risk is borderline you may decide then to have the Harmony Test as this carries no risk to the fetus.